COMPOSTOS BIOATIVOS NATURAIS: AGENTES PROMISSORES NA REDUÇÃO DO EXTRESSE OXIDATIVO E PROCESSOS INFLAMATÓRIOS

Autores

  • Rafaela da Silva Oliveira CENTRO UNIVERSITÁRIO LUTERANO DE JI-PARANÁ (CEULJI/ULBRA)
  • Claudia Perboni Lucas CENTRO UNIVERSITÁRIO LUTERANO DE JI-PARANÁ (CEULJI/ULBRA)
  • Gabrielli Antonucci CENTRO UNIVERSITÁRIO LUTERANO DE JI-PARANÁ (CEULJI/ULBRA)
  • Francisco Carlos da Silva CENTRO UNIVERSITÁRIO LUTERANO DE JI-PARANÁ (CEULJI/ULBRA)

Resumo

A quantidade excessiva de radicais livres no organismo pode desencadear um estresse oxidativo, que está relacionado a processos inflamatórios e diversas doenças degenerativas. Os compostos bioativos presentes nos vegetais podem reverter este processo, promovendo melhorias na qualidade de vida. Deste modo, esta revisão visa elucidar a ação dos compostos bioativos na redução do estresse oxidativo e nos processos inflamatórios. Para tanto, realizou-se uma pesquisa bibliográfica, através de consultas em bases de dados, utilizando descritores e critérios de inclusão e exclusão. Por meio de estudos, sabe-se que a produção de radicais livres pode ocorrer como um processo fisiológico natural ou podem ser produzidos atráves da alimentação, consumo de álcool, tabagismo etc. Para contrabalançar essa produção, o organismo possui um sistema antioxidante que pode interceptar radicais livres do metabolismo celular ou fontes exógenas. Além disso, alguns vegetais possuem compostos bioativos, especialmente compostos fenólicos, terpenóides e algumas vitaminas, que apresentam uma atividade antioxidante e antiinflamatória por meio de diversos mecanismos de ação, podendo, por exemplo, neutralizar os radicais, diminuindo o estresse oxidativo, ou até mesmo inibir a expressão de enzimas envolvidas na inflamação. Portanto, os compostos bioativos são agentes promissores para o tratamento de diversas doenças.

Biografia do Autor

Rafaela da Silva Oliveira, CENTRO UNIVERSITÁRIO LUTERANO DE JI-PARANÁ (CEULJI/ULBRA)

Técnica florestal pelo Instituto Federal de Educação, Ciências e Tecnologia de Rondônia, com estágio supervisionado no laboratório de Botânica e Ecologia Florestal do Câmpus Ji-Paraná. Graduanda em Ciências Biológicas pela Centro Universitário Luterano de Ji-Paraná- CEULJI/ULBRA

Francisco Carlos da Silva, CENTRO UNIVERSITÁRIO LUTERANO DE JI-PARANÁ (CEULJI/ULBRA)

Biólogo bacharel com ênfase em Ecologia, Licenciatura em biologia, Mestre em Genética e Toxicologia e Doutor em Biologia Celular e Molecular Aplicado a Saúde pela Universidade Luterana do Brasil. Professor Adjunto do Curso de Ciências Biológicas, Membro do Núcleo Docente Estruturante (NDE) e Conselho de Curso (CC) do Curso de Ciências Biológicas do Centro Universitário Luterano de Ji-Paraná - CEULJI/ULBRA. Tem experiência em Ecologia, Mutagênese, atuando principalmente na atividade toxicológica, genotóxica e mutagênica de produtos naturais com potencial farmacológico, estresse oxidativo e antioxidantes.

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2018-10-09

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Oliveira, R. da S., Lucas, C. P., Antonucci, G., & da Silva, F. C. (2018). COMPOSTOS BIOATIVOS NATURAIS: AGENTES PROMISSORES NA REDUÇÃO DO EXTRESSE OXIDATIVO E PROCESSOS INFLAMATÓRIOS. South American Journal of Basic Education, Technical and Technological , 5(2). Recuperado de https://teste-periodicos.ufac.br/index.php/SAJEBTT/article/view/1643

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